Acrospiroma
| Acrospiroma | |
|---|---|
| Classification and external resources | |
Micrograph showing an acrospiroma. H&E stain.
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An acrospiroma (also known as a eccrine hidradenoma, clear-cell hidradenoma,hidroacanthoma simplex, nodulocystic hidradenoma)[1]:665 is a relatively rare type ofadnexal tumor originating from the sweat gland.[2] There are several types of sweat gland-derived tumors that characterized by subtle histologic differences and slightly different clinical presentations. Generally, tumors are divided into eccrine vs aprocrine gland types. Acrospiromas were traditionally thought to display purely eccrine differentiation (akral "peripheral" + spiroma "epithelial tumor of sweat gland"), but it is now accepted that these tumors can show both eccrine and ductal apocrine differentiation. Thus, it may be more accurate to classify these tumors as "mixed" eccrine or apocrine tumors, or as hidradenomaof eccrine/apocrine sub-type. This is in contrast to more purely eccrine tumors, e.g. dermal duct tumor, hidroacanthoma simplex, or eccrine poromas.[3][4]
Acrospiromas are by definition benign, with malignant transformation very rare.[5] Surgical excision is usually curative and local recurrences are rare, although malignant tumors may metastasize.[3]
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