Adrenocorticotropic hormone deficiency
| Adrenocorticotropic hormone deficiency | |
|---|---|
| Classification and external resources | |
| ICD-10 | E23.0 |
| ICD-9 | 253.2 |
| OMIM | 201400 |
| DiseasesDB | 33423 |
Adrenocorticotropic hormone deficiency (ACTH deficiency) is a result of a decreased or absent production of adrenocorticotropic hormone (ACTH) by the pituitary gland.[1]
Presentation
Symptoms include weakness, hypoglycemia, weight loss and decreased axillary and pubic hair. It can be either isolated or part of a generalised pituary dysfunction. It can be life-threatening if not recognised.
Diagnosis
It is usually diagnosed on basis of an ACTH or insulin tolerance test in combination with the clinical symptoms.[3]
Treatment
Treatment is with hydrocortisone supplementation.
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